Publications

Independent Research (Manchester Metropolitan University)

11. “Mild, Calcium Catalysed Beckmann Rearrangements”.; Kiely-Collins, H, ;Sechi, I.; Brennan, P. E., McLaughlin, M. G.* Chem. Commun. 2018, 54, 654 [Link] 

untitled

Postdoc (University of Oxford and Institute of Cancer Research)

10. “A novel MRE11 inhibitor with activity on cell models for BRCA2 deficiency.”Folio, C.; Newman, J.; McLaughlin, M. G.; Badie, S.; Yang, H.; D’Angiolella, V. Tarsounas, M, 2017, submitted

9. “8-Substituted pyrido[3,4-d]pyrimidin-4(3H)-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone demethylase inhibitors.” Bavetsias, V.; Lanigan, R. M.; Ruda, G. F.; Atrash, B.; McLaughlin, M. G. et al. J. Med. Chem. 2016, 59, 1388 [Link]

Graduate (Queen’s University Belfast)

8. “A Hydrosilylation-Hiyama Approach to Highly Functionalized Dienes” McAdam, C. A.; McLaughlin M. G., Cook, M. J. Org. Chem. Front. 2015, 2, 510 – invited contribution for Ei-Ichi Negishi’s (Nobel Laureate) 80th Birthday [Link]

7. “MIDA-Vinylsilanes: Selective Cross-Couplings and Applications to the Synthesis of Functionalized Stilbenes” McLaughlin, M. G.; McAdam, C. A.; Cook, M. J. Org. Lett. 2015, 17, 10. [Link]

6. “Highly Diastereoselective Hydrosilylation of Allylic Alcohols”, McLaughlin, M. G.; Cook, M.J. Chem. Commun 2014, 50, 3501 [Link]

5. “Isomerization-Allylation Reaction of 1,3-Substituted Propenols” Johnston, A, J. S; McLaughlin, M. G.; Reid, J. P. Cook, M. J. Org. Biomol. Chem. 2013, 11, 7662 [Link]

4. “Platinum Catalysed Hydrosilylations of Propargylic Alcohols” McAdam, C. A.; McLaughlin, M. G.; Johnston, A. J. S.; Chen, J.; Walter, M. W.; Cook, M. J. Org. Biomol. Chem. 2013, 11, 4488 [Link]

3. “Domino Alkene Isomerisation-Claisen Rearrangement Strategy to Substituted Allyl Silanes” McLaughlin, M.G.; Cook, M. J. J. Org. Chem, 2012, 77, 2058. Highlighted as Synfact May 2012 [Link]

2. “The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols” Flanagan, J. C. A.; Dornan, L. M.; McLaughlin, M. G.; McCreanor, N. G.; Cook, M. J.; Muldoon, M. J. Green Chem. 2012, 14, 1281 [Link]

1 . “PtCl2 / Xphos ; A Highly Efficient and Readily Available Catalyst for the Regioselective Hydrometallation of Propargyl Alcohols” McLaughlin, M. G.; Cook, M. J. Chem. Commun. 2011, 47, 11104. [Link]